SCHEMBL4384467

SCHEMBL4384467

CCC(F)(C(=O)O)C(=O)CF

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 2/20 0.31
CYP1A2 P05177 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19607726 0.82 FFAR3 (0.37) FAAHCES1CES2MEN1CYP1A2
SCHEMBL29186815 0.79 FFAR3 (0.35) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2414698 0.75 ALDH1A1 (0.32) FAAHMEN1CYP1A2KMT2AALDH1A1
SCHEMBL6902951 0.73 CES2 (0.39) FAAHCES1CES2MEN1CYP1A2
SCHEMBL16207901 0.70 TSHR (0.36) FAAHALDH1A1
Lithium Ion SCHEMBL25327835 0.70
SCHEMBL5566630 0.70 CES2 (0.30) CES2
SCHEMBL1059264 0.69 ACLY (0.32) CES1ALDH1A1THRB
SCHEMBL7622632 0.68 SOAT1 (0.41) MEN1KMT2AHSD17B10ALDH1A1THRB
SCHEMBL26939980 0.67 TSHR (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571854-B1 METHOD FOR MANUFACTURING 1-ALKYL-3-DIFLUORMETHYL-5-HYDROXYPYRAZOLES BAYER IP GMBH (DE) 2014-11-05 EP claimed
EP-3060540-B1 METHOD FOR MANUFACTURING HALOGEN KETONES BAYER CROPSCIENCE AG (DE) 2018-06-27 EP disclosed
EP-3060540-A1 METHOD FOR PRODUCING HALOGEN KETONES Bayer CropScience Aktiengesellschaft (DE) 2016-08-31 EP disclosed
WO-2015059067-A1 METHOD FOR PRODUCING HALOGEN KETONES BAYER CROPSCIENCE AG (DE) 2015-04-30 WO disclosed
US-7579191-B2 Reaction method using microreactor FUJIFILM CORPORATION (JP) 2009-08-25 US disclosed
US-7434982-B2 Micro mixing and reaction device FUJIFILM CORPORATION (JP) 2008-10-14 US disclosed
US-20050036921-A1 Reaction method using microreactor FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
US-20050007872-A1 Microdevice FUJI PHOTO FILM CO., LTD. 2005-01-13 US disclosed
EP-1481724-A1 Reaction method using microreactor Fuji Photo Film Co., Ltd. (JP) 2004-12-01 EP disclosed
EP-1481723-A1 Microdevice Fuji Photo Film Co., Ltd. (JP) 2004-12-01 EP disclosed