SCHEMBL4384585

SCHEMBL4384585

O=C(Oc1ccccc1)c1ccccc1OCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
HSD17B10 Q99714 3/20 0.56
HPGD P15428 2/20 0.56
ALOX15 P16050 1/20 0.56
ALDH1A1 P00352 5/20 0.55
KMT2A Q03164 4/20 0.55
TSHR P16473 1/20 0.55
KDM4E B2RXH2 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 2/20 0.51
PTGS2 P35354 1/20 0.51
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 1/20 0.50
XBP1 P17861 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
MEN1 O00255 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7122370 0.91 MAPT (0.51) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL6284553 0.87 ALDH1A1 (0.57) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL11335428 0.85 ALDH1A1 (0.55) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL11322333 0.85 ALOX15 (0.56) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL538561 0.85 ESR1 (0.63) MAPTHSD17B10HPGDALOX15ALDH1A1
Bicarbonate SCHEMBL29983911 0.83 ESR1 (0.61) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL9574658 0.83 HSD17B10 (0.60) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL11513086 0.82 MAPT (0.52) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL4389489 0.82 HSD17B10 (0.55) MAPTHSD17B10HPGDALOX15ALDH1A1
SCHEMBL26125296 0.82 ALDH1A1 (0.55) MAPTHSD17B10HPGDALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 MAPT 1301/4885HSD17B10 963/4885HPGD 3545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.