Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153592 | 0.86 | KDM4E (0.62) | HSD17B10ALDH1A1KMT2AHTTPARP1 | |
| SCHEMBL5689805 | 0.85 | HTT (0.57) | HSD17B10ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL4384585 | 0.83 | MAPT (0.56) | HSD17B10ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL7761819 | 0.82 | KMT2A (0.58) | ALDH1A1KMT2AHTTMAPTLMNA | |
| SCHEMBL538561 | 0.82 | ESR1 (0.63) | HSD17B10ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL9574717 | 0.82 | HTT (0.73) | ALDH1A1KMT2ATSHRHTTPARP1 | |
| SCHEMBL11322333 | 0.82 | ALOX15 (0.56) | HSD17B10ALDH1A1KMT2ATSHRHTT | |
| Bicarbonate SCHEMBL29983911 | 0.81 | ESR1 (0.61) | HSD17B10ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL6284553 | 0.81 | ALDH1A1 (0.57) | HSD17B10ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL4415350 | 0.80 | HTT (0.75) | ALDH1A1KMT2ATSHRHTTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251795-B1 | NEW COMPOUNDS AND THEIR APPLICATION | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1993-01-20 | — | — | EP | disclosed |