Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943231 | 0.81 | CCR1 (0.65) | MEN1KMT2AAPAF1TDP2ALDH1A1 | |
| SCHEMBL15011055 | 0.78 | CCR1 (0.41) | NR4A2MEN1KMT2AAPAF1TDP2 | |
| SCHEMBL15010895 | 0.78 | CCR1 (0.41) | MEN1KMT2AAPAF1TDP2ALDH1A1 | |
| SCHEMBL1071707 | 0.77 | NR4A2 (0.59) | NR4A2MEN1KMT2AAPAF1TDP2 | |
| SCHEMBL4390960 | 0.75 | NR4A2 (0.57) | NR4A2MEN1KMT2AAPAF1TDP2 | |
| SCHEMBL439739 | 0.74 | CCR1 (0.39) | MEN1KMT2AAPAF1TDP2ALDH1A1 | |
| SCHEMBL440408 | 0.73 | NR4A2 (0.61) | NR4A2MEN1KMT2AAPAF1TDP2 | |
| SCHEMBL438193 | 0.73 | NR4A2 (0.51) | NR4A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL439148 | 0.73 | NR4A2 (0.40) | NR4A2MEN1KMT2AAPAF1TDP2 | |
| SCHEMBL18370996 | 0.72 | NOS2 (0.45) | MEN1KMT2AAPAF1TDP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |