Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437599 | 0.87 | CCR1 (0.42) | CCR1CCR5CCR8KMT2AMEN1 | |
| SCHEMBL440009 | 0.84 | HAVCR2 (0.38) | CCR1CCR5CCR8KMT2AMEN1 | |
| SCHEMBL441974 | 0.84 | HAVCR2 (0.38) | CCR1CCR5CCR8EPRS1KMT2A | |
| SCHEMBL439981 | 0.80 | HAVCR2 (0.55) | CCR1CCR5CCR8EPRS1KMT2A | |
| SCHEMBL441701 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL438506 | 0.74 | NR4A2 (0.44) | CCR1CCR5CCR8EPRS1KMT2A | |
| SCHEMBL436629 | 0.74 | KMT2A (0.65) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL442133 | 0.73 | BACE1 (0.41) | KMT2AMEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL437507 | 0.73 | MAP4K4 (0.35) | MAP4K4MINK1TNIK | |
| SCHEMBL439423 | 0.73 | HAVCR2 (0.36) | KMT2AMEN1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |