Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 18/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MATK | P42679 | 1/20 | 0.45 |
| ▸ | FRK | P42685 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389712 | 0.91 | PRKCQ (0.54) | PRKCQSTK17ADCLK1MAP4K4CDK1 | |
| SCHEMBL4384306 | 0.90 | PRKCQ (0.53) | PRKCQSTK17A | |
| SCHEMBL4387931 | 0.86 | PRKCQ (0.67) | PRKCQSTK17ADCLK1MAP4K4CDK1 | |
| SCHEMBL4387612 | 0.85 | PRKCQ (0.68) | PRKCQHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4379701 | 0.85 | MAPT (0.46) | PRKCQHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3179956 | 0.84 | PRKCQ (0.49) | PRKCQHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4392873 | 0.84 | PRKCQ (0.67) | PRKCQCYP3A4CYP2C9 | |
| SCHEMBL13671819 | 0.83 | PRKCQ (0.68) | PRKCQDCLK1MAP4K4CDK1CYP3A4 | |
| SCHEMBL4380044 | 0.82 | PRKCQ (0.69) | PRKCQ | |
| SCHEMBL4386385 | 0.81 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC6STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131844-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV Therapeutics Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008123891-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |