Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 13/20 | 0.67 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406390 | 0.88 | PRKCQ (0.64) | PRKCQSTK17AMAPTL3MBTL1NPC1 | |
| SCHEMBL4392873 | 0.88 | PRKCQ (0.67) | PRKCQSIRT5CYP3A4CYP2C9 | |
| SCHEMBL4384358 | 0.87 | PRKCQ (0.65) | PRKCQMAPTSIRT5GSK3B | |
| SCHEMBL4387612 | 0.87 | PRKCQ (0.68) | PRKCQSTK17ASIRT5DCLK1MAP4K4 | |
| SCHEMBL4385085 | 0.86 | PRKCQ (0.54) | PRKCQSTK17ADCLK1MAP4K4CDK1 | |
| SCHEMBL4384306 | 0.84 | PRKCQ (0.53) | PRKCQSTK17A | |
| SCHEMBL4389712 | 0.84 | PRKCQ (0.54) | PRKCQSTK17ADCLK1MAP4K4CDK1 | |
| SCHEMBL3179949 | 0.82 | PRKCQ (0.58) | PRKCQSTK17AMAPTNPC1ALDH1A1 | |
| SCHEMBL1916457 | 0.82 | STK17A (0.66) | PRKCQSTK17AMAPTNPC1ALDH1A1 | |
| SCHEMBL1916912 | 0.81 | STK17A (0.70) | PRKCQSTK17AMAPTPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131844-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV Therapeutics Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008123891-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |