Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 17/20 | 0.67 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387931 | 0.88 | PRKCQ (0.67) | PRKCQSIRT5CYP3A4CYP2C9 | |
| SCHEMBL4384358 | 0.87 | PRKCQ (0.65) | PRKCQSIRT5 | |
| SCHEMBL4384306 | 0.87 | PRKCQ (0.53) | PRKCQ | |
| SCHEMBL4380044 | 0.86 | PRKCQ (0.69) | PRKCQSIRT5CYP1A2 | |
| SCHEMBL4385085 | 0.84 | PRKCQ (0.54) | PRKCQCYP3A4CYP2C9 | |
| SCHEMBL4389712 | 0.84 | PRKCQ (0.54) | PRKCQCYP3A4CYP2C9 | |
| SCHEMBL3180778 | 0.82 | PRKCQ (0.58) | PRKCQSIRT5CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13794971 | 0.81 | PRKCQ (1.00) | PRKCQCYP3A4CYP2C9 | |
| SCHEMBL4387612 | 0.80 | PRKCQ (0.68) | PRKCQSIRT5CYP3A4CYP2C9 | |
| SCHEMBL3707444 | 0.76 | PRKCQ (0.52) | PRKCQSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131844-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV Therapeutics Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008123891-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |