Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 15/20 | 0.69 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387612 | 0.87 | PRKCQ (0.68) | PRKCQSIRT5 | |
| SCHEMBL4392873 | 0.86 | PRKCQ (0.67) | PRKCQSIRT5CYP1A2 | |
| SCHEMBL4384358 | 0.86 | PRKCQ (0.65) | PRKCQSIRT5 | |
| SCHEMBL4384306 | 0.85 | PRKCQ (0.53) | PRKCQ | |
| SCHEMBL3182583 | 0.84 | PRKCQ (0.61) | PRKCQNTRK1SIRT5 | |
| SCHEMBL4385085 | 0.82 | PRKCQ (0.54) | PRKCQ | |
| SCHEMBL4389712 | 0.82 | PRKCQ (0.54) | PRKCQ | |
| SCHEMBL13671808 | 0.82 | PRKCQ (0.86) | PRKCQ | |
| SCHEMBL13793818 | 0.82 | PRKCQ (1.00) | PRKCQ | |
| SCHEMBL4385162 | 0.80 | NTRK1 (0.49) | PRKCQNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131844-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV Therapeutics Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008123891-A1 | PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS | CV THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |