Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378557 | 0.83 | POLB (0.42) | HRH3FFAR1ALDH1A1LMNA | |
| SCHEMBL4385206 | 0.82 | KDM4E (0.39) | HRH3PPARGPPARAFFAR1ALDH1A1 | |
| SCHEMBL4378585 | 0.81 | ALDH1A1 (0.53) | HRH3FFAR1ALDH1A1LMNA | |
| SCHEMBL4383472 | 0.81 | ALDH1A1 (0.46) | HRH3PPARGPPARACYP4F2CYP4A11 | |
| SCHEMBL4376187 | 0.80 | L3MBTL1 (0.59) | HRH3ALDH1A1LMNA | |
| SCHEMBL4383862 | 0.80 | ALDH1A1 (0.46) | HRH3PPARGPPARAFFAR1ALDH1A1 | |
| Oxalic Acid SCHEMBL7990912 | 0.79 | MEN1 (0.47) | HRH3PPARAFFAR1ALDH1A1LMNA | |
| SCHEMBL7991257 | 0.78 | CYP3A4 (0.45) | ALDH1A1LMNA | |
| SCHEMBL4378580 | 0.78 | KDM4E (0.43) | HRH3ALDH1A1LMNA | |
| SCHEMBL4376133 | 0.78 | HRH3 (0.46) | HRH3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |