Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735328 | 0.82 | GRIN2D (0.59) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14856654 | 0.82 | GRIN2D (0.59) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24106000 | 0.78 | GRIN2D (0.50) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1150398 | 0.77 | TSHR (0.56) | TSHREPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12943286 | 0.77 | PKM (0.42) | EPHX2 | |
| SCHEMBL812583 | 0.77 | EPHX2 (0.46) | TSHREPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13287394 | 0.75 | GRIN2D (0.65) | TSHREPHX2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7713102 | 0.75 | TSHR (0.55) | TSHREPHX2GRIN2DGRIN3BGRIN1 | |
| Memantine SCHEMBL1377007 | 0.74 | GRIN1 (0.61) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| Acetic Acid SCHEMBL323053 | 0.74 | DPP4 (0.39) | TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989177-B1 | AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2012-08-01 | — | — | EP | disclosed |
| EP-1989177-B1 | AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-20090299096-A1 | Amidoadamantanes and Method for Producing the Same | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20090299096-A1 | Amidoadamantanes and Method for Producing the Same | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20090299096-A1 | Amidoadamantanes and Method for Producing the Same | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2009-12-03 | — | — | US | disclosed |
| EP-1989177-A1 | AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME | Justus-Liebig-Universität Giessen (DE) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007101535-A1 | AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007101535-A1 | AMIDOADAMANTANES AND METHOD FOR PRODUCING THE SAME | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299096-A1 | Amidoadamantanes and Method for Producing the Same | ADORA3, TAAR5, ADORA1 | TSHR 246/4885EPHX2 1578/4885GRIN2D 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.