Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108876 | 0.93 | ABL1 (0.48) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6828591 | 0.84 | HPGD (0.65) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8984742 | 0.83 | MEN1 (0.47) | NPC1MAPTRAB9AEDNRAEDNRB | |
| SCHEMBL4272491 | 0.81 | ESR1 (0.45) | SMN1; SMN2GAACYP3A4ALDH1A1 | |
| SCHEMBL4270501 | 0.81 | ESR1 (0.32) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1034459 | 0.81 | HSD17B10 (0.38) | TP53CYP3A4ALDH1A1 | |
| SCHEMBL573085 | 0.80 | KMT2A (0.47) | ABL1ABCB1BCRGAAKMT2A | |
| SCHEMBL1289717 | 0.80 | CHRNB2 (0.33) | ALDH1A1 | |
| SCHEMBL5813609 | 0.79 | ESR1 (0.40) | HPGDALDH1A1KMT2A | |
| SCHEMBL8981615 | 0.79 | TSHR (0.34) | NPC1MAPTRAB9AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629429-B2 | Aromatic resin; optical device; overcoating substrate with polymer; charge transfer compound, charge generating compoind | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-12-08 | — | — | US | disclosed |
| US-20040158017-A1 | Substituted fluorene polymers their preparation and uses | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-08-12 | — | — | US | disclosed |
| EP-1385919-B1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2004-08-11 | — | — | EP | disclosed |