SCHEMBL5813609

SCHEMBL5813609

CCOCCOc1ccc(-c2cccc3c2C(c2ccc(OCCOCC)cc2)c2ccccc2-3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
GPR174 Q9BXC1 5/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NCF1 P14598 2/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
KCNH2 Q12809 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
THRA P10827 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5796673 0.87 L3MBTL1 (0.42) ESR1ESR2GPR174L3MBTL1NCF1
SCHEMBL4272491 0.86 ESR1 (0.45) ESR1ESR2CHRNB4CHRNA3CHRNA7
SCHEMBL4385697 0.79 NPC1 (0.51) ALDH1A1HPGDKMT2A
SCHEMBL5171759 0.78 THRB (0.53) ESR1ESR2GPR174PPARGPPARA
SCHEMBL9069717 0.76 TDP1 (0.49) ESR1ESR2GPR174PPARGALDH1A1
SCHEMBL19149038 0.75 ALDH1A1 (0.36) ESR1ESR2CHRNB4CHRNA3CHRNA7
SCHEMBL8984742 0.74 MEN1 (0.47) L3MBTL1ALDH1A1KMT2A
SCHEMBL577071 0.74 ALDH1A1 (0.53) ESR1ESR2GPR174PPARGPPARA
SCHEMBL30985950 0.74 ALDH1A1 (0.53) ESR1ESR2GPR174PPARGPPARA
SCHEMBL28108876 0.73 ABL1 (0.48) ESR1ESR2HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006096399-A2 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-14 WO disclosed