Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065007 | 0.88 | AR (0.37) | ARMAPTPRKCZRAB9AGAA | |
| SCHEMBL4374929 | 0.78 | MAPT (0.39) | ARMAPTPRKCZRAB9AGAA | |
| SCHEMBL4370270 | 0.74 | GRIA4 (0.44) | ARMAPTPRKCZKDM4EALDH1A1 | |
| SCHEMBL4381278 | 0.72 | AR (0.39) | ARMAPTPRKCZRAB9AGAA | |
| SCHEMBL13863268 | 0.71 | AR (0.41) | ARMAPTPRKCZKDM4EALDH1A1 | |
| SCHEMBL4370222 | 0.68 | AR (0.39) | ARMAPTPRKCZKDM4EALDH1A1 | |
| SCHEMBL24208929 | 0.68 | MAPT (0.62) | ARMAPTPRKCZRAB9AGAA | |
| SCHEMBL6065003 | 0.67 | PRKCZ (0.39) | ARMAPTPRKCZRAB9AGAA | |
| SCHEMBL4386445 | 0.67 | GRIA4 (0.36) | ARMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL4369440 | 0.66 | ALDH1A1 (0.43) | MAPTGAAKDM4EALDH1A1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670757-B1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-05-06 | — | — | EP | disclosed |