Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064335 | 0.89 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL2961961 | 0.86 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL810779 | 0.79 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL811151 | 0.79 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL810343 | 0.79 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL5067776 | 0.78 | PDE7A (0.53) | MAPTALDH1A1SMN1; SMN2TDP1NPSR1 | |
| SCHEMBL809916 | 0.77 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL811364 | 0.76 | AGER (0.52) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4382272 | 0.76 | MAOA (0.49) | MAPTALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL811413 | 0.74 | PDE7A (0.48) | MAPTALDH1A1MAOAMAOBPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094276-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008133753-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2008-11-06 | — | — | WO | disclosed |
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |