Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.53 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810198 | 0.89 | PDE7A (0.55) | PDE7APDE7BNPC1RAB9AMAPT | |
| SCHEMBL5069003 | 0.79 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4386633 | 0.78 | MAPT (0.46) | PDE7APDE7BMAPTALDH1A1MEN1 | |
| SCHEMBL5064335 | 0.78 | MAPT (0.41) | PDE7APDE7BMAPTALDH1A1MEN1 | |
| SCHEMBL11490846 | 0.77 | MAPT (0.66) | NPC1RAB9ACYP11B1CYP11B2MAPT | |
| SCHEMBL811556 | 0.76 | PDE7A (0.53) | PDE7APDE7BMAPTALDH1A1MEN1 | |
| SCHEMBL2968510 | 0.75 | PDE7A (0.68) | PDE7APDE7BMAPTALDH1A1MEN1 | |
| SCHEMBL18702665 | 0.74 | MAPT (0.51) | NPC1RAB9ACYP11B1CYP11B2MAPT | |
| SCHEMBL5067747 | 0.74 | PIN1 (0.54) | NPC1RAB9ACYP11B1CYP11B2CA12 | |
| SCHEMBL29502991 | 0.74 | MAPT (0.51) | NPC1RAB9ACYP11B1CYP11B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |