Biphenyl

Biphenyl

SCHEMBL4386676

CCCCCC[PH+](CCCCCC)CCCCCC.c1ccc(-c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.37
MMP9 P14780 2/20 0.37
MEN1 O00255 2/20 0.36
TP53 P04637 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTPN1 P18031 1/20 0.36
MGLL Q99685 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
TSHR P16473 1/20 0.35
DNM1 Q05193 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699496 0.89 TSHR (0.35) MEN1KMT2AMAPTPTPN1SMN1; SMN2
Octane SCHEMBL18395350 0.84 DNM1 (0.44) MEN1TP53KMT2ASMN1; SMN2HTT
Octane SCHEMBL23754774 0.82 DNM1 (0.42) MEN1TP53KMT2ACYP1A2CYP2D6
SCHEMBL25312239 0.81 ALDH1A1 (0.34) TP53SMN1; SMN2KDM4ELMNA
SCHEMBL701476 0.79 CES2 (0.36) MEN1TP53KMT2AMAPTSMN1; SMN2
SCHEMBL10434550 0.78 LTA4H (0.39) MEN1TP53KMT2AMAPTSMN1; SMN2
Hexadecane SCHEMBL8524813 0.78 ALDH1A1 (0.53) MMP2MMP9MEN1TP53KMT2A
Dodecane SCHEMBL27916009 0.78 ALDH1A1 (0.53) MMP2MMP9MEN1TP53KMT2A
Biphenyl SCHEMBL5868587 0.78 ALDH1A1 (0.53) MMP2MMP9MEN1TP53KMT2A
Biphenyl SCHEMBL27853080 0.78 ALDH1A1 (0.53) MMP2MMP9MEN1TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629431-B2 Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate IDEMITSU KOSAN CO., LTD. (JP) 2009-12-08 US disclosed
US-7390868-B2 Catalyst for polycarbonate production and process for producing polycarbonate NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-06-24 US disclosed
US-20080064847-A1 Oxidative carbonylation; molecular weight control IDEMISU KOSAN CO., LTD. (JP) 2008-03-13 US disclosed
US-20070043199-A1 Catalyst for polycarbonate production and process for producing polycarbonate IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed