SCHEMBL4386837

SCHEMBL4386837

c1ccc2c(-c3nnc[nH]3)cccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.41
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
KDM4E B2RXH2 5/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALOX15 P16050 2/20 0.39
ALPL P05186 1/20 0.39
GAA P10253 1/20 0.39
GSK3B P49841 1/20 0.37
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37
MAPK13 O15264 1/20 0.37
GCGR P47871 1/20 0.37
MAPK12 P53778 1/20 0.37
MAPK11 Q15759 1/20 0.37
MAPK14 Q16539 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28815137 0.78 KDM4E (0.37) KDM4ECYP1A2CYP3A4CYP2C19MAPK11
SCHEMBL186872 0.76 PI4KA (0.49) NISCHPI4KAPI4K2BPI4K2API4KB
SCHEMBL24317556 0.75 PI4KA (0.47) NISCHPI4KAPI4K2BPI4K2API4KB
SCHEMBL12887908 0.74 IDO1 (0.31) ALDH1A1L3MBTL1
SCHEMBL11121507 0.73 DCUN1D1 (0.50) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL297803 0.73 ALDH1A1 (0.52) KDM4ECYP3A4ALOX15GAAALDH1A1
SCHEMBL12765039 0.71 PIM1 (0.45)
SCHEMBL450794 0.70 TGFBR1 (0.39) KDM4ECYP1A2CYP3A4CYP2C19GSK3B
SCHEMBL51007 0.70 ADRA2A (0.54) NISCHPI4KAPI4K2BPI4K2API4KB
SCHEMBL1250423 0.70 KDM4E (0.42) NISCHPI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8314545-B2 Organic electroluminescence element PANASONIC CORPORATION (JP) 2012-11-20 US claimed
EP-1881543-B1 ORGANIC ELECTROLUMINESCENT ELEMENT PANASONIC CORP (JP) 2015-07-08 EP disclosed
US-8314545-B2 Organic electroluminescence element PANASONIC CORPORATION (JP) 2012-11-20 US disclosed
CN-101343234-B Aromatic amine derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO 2012-08-15 CN disclosed
CN-102603688-A Electroluminescent device CIBA SC HOLDING AG 2012-07-25 CN disclosed
CN-102516090-A Aromatic amine derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO 2012-06-27 CN disclosed
CN-101142169-B Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO.,LTD. (JP) 2011-12-21 CN disclosed
CN-101142170-B Aromatic amine derivative and organic electroluminescent element using the same IDEMITSU PETROCHEMICAL CO 2011-04-13 CN disclosed
CN-100514701-C Organic EL element FUJI ELECTRIC HOLDINGS (JP) 2009-07-15 CN disclosed
CN-101421225-A Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-04-29 CN disclosed
CN-1271044-C Arylamine compound and organic electroluminescent device IDEMITSU KOSAN CO (JP) 2006-08-23 CN disclosed
CN-1271167-C Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2006-08-23 CN disclosed
CN-1775737-A Arylamine compound and organic electroluminescent device IDEMITSU KOSAN CO (JP) 2006-05-24 CN disclosed
CN-1721499-A Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2006-01-18 CN disclosed
CN-1219747-C Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2005-09-21 CN disclosed
CN-1174078-C Organic electroluminescent device ������������ʽ���� 2004-11-03 CN disclosed
CN-1388801-A Novel arylamine compound and organic electroluminescent device IDEMITSU KOSAN CO (JP) 2003-01-01 CN disclosed
CN-1327468-A Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2001-12-19 CN disclosed
CN-1327469-A Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2001-12-19 CN disclosed
CN-1292022-A Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2001-04-18 CN disclosed