SCHEMBL4387212

SCHEMBL4387212

C[C@H](NO)C(=O)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ELANE P08246 2/20 0.50
ALDH1A1 P00352 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
THRB P10828 1/20 0.42
GFER P55789 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
MAPK1 P28482 1/20 0.42
HPGD P15428 1/20 0.41
MTNR1A P48039 4/20 0.41
MTNR1B P49286 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11018852 1.00 ATM (0.50) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL28760385 0.85 ELANE (0.50) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL16894676 0.85 ELANE (0.50) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL1697079 0.85 ELANE (0.50) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL27535714 0.83 L3MBTL1 (0.49) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL363021 0.81 ELANE (0.47) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL2968424 0.81 MTNR1A (0.54) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL8583451 0.80 MAPK1 (0.49) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL5324073 0.80 ELANE (0.46) ATML3MBTL1ELANEALDH1A1KMT2A
SCHEMBL6250510 0.80 MAPK1 (0.49) ATML3MBTL1ELANEALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-212432989-U P hydroxy phenyl alanine urine detection test paper box and test paper subassembly 苏州良辰生物仪器试剂有限公司 2021-01-29 CN claimed
CN-112213485-A Magnetic nano-microsphere as p-hydroxy phenylalanine urine detection reagent and preparation method thereof 南京迪安医学检验所有限公司 2021-01-12 CN claimed
CN-1193979-A Macrolide compounds NOVARTIS AG (CH) 1998-09-23 CN claimed
CN-212514284-U P-hydroxy phenylalanine urine detection test paper box and test paper assembly 苏州良辰生物仪器试剂有限公司 2021-02-09 CN disclosed
CN-212432989-U P hydroxy phenyl alanine urine detection test paper box and test paper subassembly 苏州良辰生物仪器试剂有限公司 2021-01-29 CN disclosed
CN-212432989-U P hydroxy phenyl alanine urine detection test paper box and test paper subassembly 苏州良辰生物仪器试剂有限公司 2021-01-29 CN disclosed
CN-212432989-U P hydroxy phenyl alanine urine detection test paper box and test paper subassembly 苏州良辰生物仪器试剂有限公司 2021-01-29 CN disclosed
CN-211627380-U Convenient p hydroxy phenyl alanine urine detection test paper box that detects 江苏东博生物医药有限公司 2020-10-02 CN disclosed
CN-211627380-U Convenient p hydroxy phenyl alanine urine detection test paper box that detects 江苏东博生物医药有限公司 2020-10-02 CN disclosed
CN-211627380-U Convenient p hydroxy phenyl alanine urine detection test paper box that detects 江苏东博生物医药有限公司 2020-10-02 CN disclosed
CN-211426281-U Anti-falling p-hydroxyphenylalanine urine detection kit 江苏东博生物医药有限公司 2020-09-04 CN disclosed
EP-1903108-B1 Transmembrane domain-removed recombinant human tyrosinase and method of producing the same UNIV CHUNG ANG IND (KR) 2009-12-02 EP disclosed
US-20080124758-A1 Transmembrane domain removed recombinant human tyrosinase and method of producing the same CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) 2008-05-29 US disclosed
EP-1903108-A1 Transmembrane domain-removed recombinant human tyrosinase and method of producing the same Chung-Ang University Industry-Academy Cooperation Foundation (KR) 2008-03-26 EP disclosed
CN-1193979-A Macrolide compounds NOVARTIS AG (CH) 1998-09-23 CN disclosed
EP-0594645-A1 PROCESS FOR THE PREPARATION OF PURE ISOMERIC FORMS OF 3,3,5-TRIMETHYL CYCLOHEXANOL AND 3,3,5-TRIMETHYL CYCLOHEXANONE AMINO ACID ESTERS PANMEDICA (FR) 1994-05-04 EP disclosed
WO-1992022529-A1 PROCESS FOR THE PREPARATION OF PURE ISOMERIC FORMS OF 3,3,5-TRIMETHYL CYCLOHEXANOL AND 3,3,5-TRIMETHYL CYCLOHEXANONE AMINO ACID ESTERS PANMEDICA (FR) 1992-12-23 WO disclosed
EP-0261017-B1 AMINO ACID ESTERS OF CYCLOALIPHATIC ALCOHOLS, PROCESS FOR THEIR PREPARATION AND USE AS MEDICINE PANMEDICA S.A. (FR) 1991-03-20 EP disclosed
EP-0261017-A1 Amino acid esters of cycloaliphatic alcohols, process for their preparation and use as medicine PANMEDICA S.A. (FR) 1988-03-23 EP disclosed
US-3725470-A AMINO ACID DERIVATIVES HOFFMANN LA ROCHE 1973-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124758-A1 Transmembrane domain removed recombinant human tyrosinase and method of producing the same TYR, TH, TMX1 ATM 4620/4885L3MBTL1 4114/4885ELANE 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.