SCHEMBL2968424

SCHEMBL2968424

CC(=O)N[C@@H](C)C(=O)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 7/20 0.54
MTNR1B P49286 7/20 0.54
ACACB O00763 3/20 0.49
ACACA Q13085 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
ATM Q13315 1/20 0.47
ELANE P08246 1/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28231874 0.97 MTNR1A (0.51) MTNR1AMTNR1BACACBACACAL3MBTL1
SCHEMBL27535714 0.87 L3MBTL1 (0.49) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT
SCHEMBL6250510 0.84 MAPK1 (0.49) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT
SCHEMBL8583451 0.84 MAPK1 (0.49) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT
SCHEMBL10791981 0.83 ELANE (0.53) ALDH1A1ELANEMEN1LMNAGAA
SCHEMBL7901353 0.82 RECQL (0.56) ACACBL3MBTL1ALDH1A1MAPTMEN1
SCHEMBL11018852 0.81 ATM (0.50) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT
SCHEMBL4387212 0.81 ATM (0.50) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT
SCHEMBL16894676 0.81 ELANE (0.50) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT
SCHEMBL1697079 0.81 ELANE (0.50) MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110196335-A Biomarker relevant to renal function and its application method 梅塔博隆股份有限公司 2019-09-03 CN claimed
CN-109715185-A Water soluble and chemically stable glucagon peptides 印第安纳大学研究及科技有限公司 2019-05-03 CN claimed
CN-109689079-A Bovine fibroblast growth factor 21 and ketosis in dairy cattle 伊兰科美国公司 2019-04-26 CN claimed
EP-2831036-B1 PROCESS FOR PREPARING FLUOROLEUCINE ALKYL ESTERS INTERVET INT BV (NL) 2018-09-12 EP claimed
CN-108350025-A additive system for protein PEGylation 百时美施贵宝公司 2018-07-31 CN claimed
CN-104619349-B Prostate specific membrane antigen antibody drug conjugates AMBRX公司 2018-07-10 CN claimed
CN-107674121-A Bovine somatotropin polypeptide and its purposes by modification AMBRX 公司 2018-02-09 CN claimed
CN-107614010-A It is bound to the antibody drug conjugates (ADC) of FLT3 albumen 艾更斯司股份有限公司 2018-01-19 CN claimed
CN-104163864-B Through modifying the polypeptides of FGF 21 and its purposes AMBRX公司 2017-08-01 CN claimed
CN-101663046-B modified FGF-21 polypeptides and uses thereof AMBRX公司 2017-07-28 CN claimed
CN-102703446-A Compositions of trna and uses thereof AMBRX INC 2012-10-03 CN claimed
CN-101087875-B Compositions of aminoacyl-tRNA synthetases and uses thereof AMBRX INC 2012-08-22 CN claimed
CN-102459325-A Gastrostatin receptor activated glucagon compounds UNIV INDIANA RES & TECH CORP 2012-05-16 CN claimed
CN-102325539-A Amide based glucagon superfamily peptide prodrugs UNIV INDIANA RES & TECH CORP 2012-01-18 CN claimed
CN-102307905-A Production of carrier-peptide conjugates using chemically reactive unnatural amino acids SCRIPPS RESEARCH INST 2012-01-04 CN claimed
CN-101983066-A Ester-based peptide prodrugs UNIV INDIANA RES & TECH CORP 2011-03-02 CN claimed
CN-101384711-A Non-natural amino acid polypeptides having modulated immunogenicity AMBRX INC (US) 2009-03-11 CN claimed
CN-101273140-A tRNA compositions and uses thereof AMBRX INC (US) 2008-09-24 CN claimed
CN-101265298-A Endothelium chalone mutant containing non-natural amino acid and derivatives thereof UNIV CHINA PHARMA (CN) 2008-09-17 CN claimed
CN-101087875-A Compositions of aminoacyl-tRNA synthetases and uses thereof AMBRX INC (US) 2007-12-12 CN claimed