Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683151 | 0.89 | SMN1; SMN2 (0.47) | CLCN2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3324739 | 0.84 | CLCN2 (0.39) | CLCN2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29155872 | 0.84 | SCN1A (0.44) | CLCN2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL129586 | 0.84 | CLCN2 (0.50) | CLCN2HMGB1GABRA1GABRB2FOLH1 | |
| SCHEMBL269921 | 0.82 | CLCN2 (0.43) | CLCN2MEN1KMT2AHMGB1GABRA1 | |
| SCHEMBL30274134 | 0.82 | TP53 (0.45) | CLCN2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7101456 | 0.81 | MMP2 (0.50) | CLCN2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL10399130 | 0.80 | GABRA1 (0.48) | MEN1KMT2AL3MBTL1GABRA1GABRB2 | |
| SCHEMBL12427635 | 0.78 | HTT (0.50) | MEN1KMT2AHMGB1ALDH1A1TP53 | |
| SCHEMBL27181946 | 0.77 | CLCN2 (0.44) | CLCN2MEN1KMT2AHMGB1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2923689-B1 | Dental composition | DENTSPLY DETREY GMBH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3122311-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015144579-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2015-10-01 | — | — | WO | disclosed |
| EP-2923689-A1 | Dental composition | DENTSPLY DETREY GmbH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-7968614-B2 | Macromer composition including light activated initiator | SURMODICS, INC. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-1893162-A2 | MACROMER COMPOSITION INCLUDING LIGHT ACTIVATED INITIATOR | SurModics, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006138542-A2 | MACROMER COMPOSITION INCLUDING LIGHT ACTIVATED INITIATOR | SURMODICS, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060287410-A1 | Macromer composition including light activated initiator | SURMODICS, INC. | 2006-12-21 | — | — | US | disclosed |