SCHEMBL7101456

SCHEMBL7101456

CCN(CC)c1c(N)cccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.50
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
ALDH1A1 P00352 6/20 0.41
HSD17B10 Q99714 5/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CDC25B P30305 1/20 0.40
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683151 0.87 SMN1; SMN2 (0.47) MMP2MEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL7103100 0.84 ALDH1A1 (0.47) MMP2MEN1KMT2AG6PDCASP7
SCHEMBL10455717 0.82 MMP2 (0.57) MMP2KMT2ASMN1; SMN2G6PDCASP7
SCHEMBL9695883 0.81 ALDH1A1 (0.64) MEN1KMT2ASMN1; SMN2ALDH1A1HSD17B10
SCHEMBL43874 0.81 CLCN2 (0.49) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL30274134 0.81 TP53 (0.45) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL7655945 0.79 ALDH1A1 (0.44) SMN1; SMN2L3MBTL1CASP7ALDH1A1HSD17B10
SCHEMBL28228530 0.77 GABRP (0.41) MMP2MEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL27835542 0.77 GABRP (0.41) MMP2MEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL12427635 0.77 HTT (0.50) MEN1KMT2AALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0971991-B1 INK ADDITIVES AVECIA LTD (GB) 2003-09-03 EP disclosed
US-6319309-B1 FOR INK JET PRINTING INKS TO GIVE IMAGES HAVING HIGH WATER FASTNESS AND GOOD OPTICAL DENSITY AVECIA LIMITED (GB) 2001-11-20 US disclosed
US-6254669-B1 Bleed reduction agents for ink printing inks ZENECA LIMITED (GB) 2001-07-03 US disclosed
EP-0971991-A1 INK ADDITIVES Avecia Limited (GB) 2000-01-19 EP disclosed
EP-0966451-A1 BLEED REDUCTION AGENTS FOR INK JET PRINTING INKS ZENECA LIMITED (GB) 1999-12-29 EP disclosed
WO-1998044057-A1 INK ADDITIVES AVECIA LIMITED (GB) 1998-10-08 WO disclosed
WO-1998034926-A1 BLEED REDUCTION AGENTS FOR INK JET PRINTING INKS AVECIA LIMITED (GB) 1998-08-13 WO disclosed