Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | GUSB | P08236 | 3/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428642 | 1.00 | MAOA (0.45) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL18740730 | 0.81 | MAOA (0.45) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL11761585 | 0.80 | POLB (0.47) | POLBALDH1A1C1RKMT2ATDP1 | |
| SCHEMBL3085387 | 0.79 | KDM4E (0.67) | MAPTKDM4EPOLBRAB9AL3MBTL1 | |
| SCHEMBL7417644 | 0.79 | KDM4E (0.45) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL6534285 | 0.79 | KDM4E (0.66) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL6534280 | 0.79 | KDM4E (0.66) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL29951387 | 0.78 | ERN1 (0.47) | MAPTKDM4EPOLBRAB9AL3MBTL1 | |
| SCHEMBL27260118 | 0.78 | TERT (0.43) | MAOAMAOBCYP1A2ALDH1A1GUSB | |
| SCHEMBL9071311 | 0.78 | ERN1 (0.47) | MAPTKDM4EPOLBRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011977-A1 | Novel Lipopeptides as Antibacterial Agents | HILL JASON | 2009-01-08 | — | — | US | disclosed |
| US-20080287347-A1 | Novel Lipopeptides as Antibacterial Agents | CUBIST PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20040067878-A1 | Novel lipopeptides as antibacterial agents | MERCK SHARP & DOHME CORP. | 2004-04-08 | — | — | US | disclosed |
| CN-1423656-A | Lipopeptides as antibacterial agents | CUBIST PHARM INC (US) | 2003-06-11 | — | — | CN | disclosed |
| EP-1246838-A1 | LIPOPEPTIDES AS ANTIBACTERIAL AGENTS | Cubist Pharmaceuticals, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001044274-A1 | LIPOPEPTIDES AS ANTIBACTERIAL AGENTS | CUBIST PHARMACEUTICALS, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287347-A1 | Novel Lipopeptides as Antibacterial Agents | CLPTM1, NGLY1, VIP | MAOA 3950/4885MAOB 3672/4885MAPT 4381/4885 |
| US-20040067878-A1 | Novel lipopeptides as antibacterial agents | CLPTM1, NGLY1, VIP | MAOA 3950/4885MAOB 3672/4885MAPT 4381/4885 |
| US-20090011977-A1 | Novel Lipopeptides as Antibacterial Agents | CLPTM1, NGLY1, VIP | MAOA 3950/4885MAOB 3672/4885MAPT 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.