Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | C1R | P00736 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085387 | 0.81 | KDM4E (0.67) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL24695915 | 0.81 | KDM4E (0.41) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL20417193 | 0.81 | KDM4E (0.41) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL28236229 | 0.80 | ELANE (0.42) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL9071311 | 0.79 | ERN1 (0.47) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL29951387 | 0.79 | ERN1 (0.47) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL31428642 | 0.79 | MAOA (0.45) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL4387472 | 0.79 | MAOA (0.45) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL8987365 | 0.78 | ALDH1A1 (0.51) | KDM4EMAPTRAB9APOLBL3MBTL1 | |
| SCHEMBL27599168 | 0.77 | KDM4E (0.58) | KDM4EMAPTRAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946000-A | Synthesis method of 1-methyl-2-oxo-1, 2-dihydro-4-quinolinecarboxylic acid methyl ester | 南通大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946000-A | Synthesis method of 1-methyl-2-oxo-1, 2-dihydro-4-quinolinecarboxylic acid methyl ester | 南通大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-110062757-B | Factor XIa inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3344604-B1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-106478500-B | Carboxylic acid substituted (hetero) aromatic ring derivatives, and preparation method and application thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-04-23 | — | — | US | disclosed |
| WO-2018133793-A1 | BLOOD COAGULATION FACTOR XIA INHIBITOR AND USES THEREOF | 广东东阳光药业有限公司 | 2018-07-26 | — | — | WO | disclosed |
| EP-3344604-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017036404-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-09 | — | — | WO | disclosed |
| CN-106478500-A | Carboxylic acid-substituted（Miscellaneous）Aromatic ring analog derivative and its production and use | 广东东阳光药业有限公司 | 2017-03-08 | — | — | CN | disclosed |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM2, PIM1, CDK2 | KDM4E 2503/4885MAPT 3191/4885RAB9A 1941/4885 |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | XDH, ABCG2, SLC7A1 | KDM4E 2400/4885MAPT 3465/4885RAB9A 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.