Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944734 | 0.89 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBCA2 | |
| SCHEMBL30389113 | 0.89 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBCA2 | |
| SCHEMBL28894056 | 0.85 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL8400879 | 0.82 | HTT (0.38) | NPC1RAB9ALMNACA2ATM | |
| SCHEMBL4398146 | 0.81 | KDM4E (0.36) | NPC1RAB9ALMNAPOLBCA2 | |
| SCHEMBL7141288 | 0.77 | POLB (0.47) | NPC1RAB9ALMNAPOLBATM | |
| SCHEMBL2231426 | 0.77 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBCA2 | |
| SCHEMBL6035514 | 0.76 | NPC1 (0.36) | NPC1RAB9ALMNAPOLBATM | |
| SCHEMBL3320509 | 0.76 | RAB9A (0.43) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL3320508 | 0.76 | RAB9A (0.37) | NPC1RAB9ALMNACA2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298978-A1 | Stabilized organic materials containing fillers | CIBA SPECIALTY CHEMICALS CORP. | 2009-12-03 | — | — | US | disclosed |
| US-5965641-A | A STERICALLY HINDERED PIPERIDINE COMPOUND, OR AN OLIGOMERIC OR POLYMERIC STERICALLY HINDERED PIPERIDINE COMPOUND CONTAINING ONE OR SEVERAL TRIAZINE UNITS; RADIATION RESISTANCE, OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |