Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398146 | 0.88 | KDM4E (0.36) | HTTKDM4EHPGDSHBGPPARG | |
| SCHEMBL4387585 | 0.82 | NPC1 (0.37) | KDM4ESHBGCA2ATMNPC1 | |
| SCHEMBL27341518 | 0.82 | GABRA1 (0.45) | HTTKDM4EHPGDPPARGPPARA | |
| SCHEMBL30389113 | 0.79 | NPC1 (0.40) | HTTKDM4EHPGDSHBGPPARG | |
| SCHEMBL2944734 | 0.79 | NPC1 (0.40) | HTTKDM4EHPGDSHBGPPARG | |
| SCHEMBL9488921 | 0.78 | ALDH1A1 (0.44) | HTTKDM4EHPGDPPARGPPARA | |
| SCHEMBL8415489 | 0.77 | KDM4E (0.45) | HTTKDM4EHPGDPPARGPPARA | |
| SCHEMBL3320508 | 0.77 | RAB9A (0.37) | HTTKDM4EHPGDSHBGPPARG | |
| SCHEMBL7900910 | 0.76 | NPC1 (0.42) | HTTKDM4EHPGDSHBGPPARG | |
| SCHEMBL11470802 | 0.75 | CNR1 (0.35) | KDM4EHPGDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965641-A | A STERICALLY HINDERED PIPERIDINE COMPOUND, OR AN OLIGOMERIC OR POLYMERIC STERICALLY HINDERED PIPERIDINE COMPOUND CONTAINING ONE OR SEVERAL TRIAZINE UNITS; RADIATION RESISTANCE, OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |