Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990234 | 0.87 | RAB9A (0.38) | RAB9ANPC1LMNAALDH1A1TSHR | |
| SCHEMBL28884858 | 0.83 | NPC1 (0.41) | RAB9ANPC1LMNAALDH1A1KDM4E | |
| SCHEMBL1956396 | 0.83 | ALDH1A1 (0.50) | RAB9ANPC1LMNAALDH1A1TSHR | |
| SCHEMBL28894056 | 0.80 | NPC1 (0.38) | RAB9ANPC1LMNAALDH1A1TDP1 | |
| SCHEMBL2944734 | 0.80 | NPC1 (0.40) | RAB9ANPC1LMNAALDH1A1TDP1 | |
| SCHEMBL30389113 | 0.80 | NPC1 (0.40) | RAB9ANPC1LMNAALDH1A1TDP1 | |
| SCHEMBL7900910 | 0.79 | NPC1 (0.42) | RAB9ANPC1LMNAALDH1A1TSHR | |
| SCHEMBL7141288 | 0.79 | POLB (0.47) | RAB9ANPC1LMNAALDH1A1TSHR | |
| SCHEMBL28507848 | 0.78 | KDM4E (0.41) | RAB9ANPC1LMNAALDH1A1TSHR | |
| SCHEMBL27622566 | 0.78 | NPC1 (0.35) | RAB9ANPC1LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100119461-A1 | ANTIMICROBIAL COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| US-6893245-B2 | Apparatus for preparing an eyeglass lens having a computer system controller | Q2100, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-6557734-B2 | Plastic lens systems, compositions, and methods | Q2100, INC. | 2003-05-06 | — | — | US | disclosed |
| US-20010048002-A1 | Plastic lens systems, compositions, and methods | OPTICAL DYNAMICS CORP. | 2001-12-06 | — | — | US | disclosed |
| EP-0683200-A1 | Stabilizer composition | GENERAL ELECTRIC COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119461-A1 | ANTIMICROBIAL COMPOSITION | ZFR, SOD1, NISCH | RAB9A 2209/4885NPC1 2025/4885LMNA 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.