SCHEMBL4387600

SCHEMBL4387600

N#CCCN1CCC(CCCC2CCN(CCC#N)CC2)CC1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
PKM P14618 1/20 0.58
POLB P06746 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.48
MAPT P10636 4/20 0.44
GAA P10253 4/20 0.38
TSHR P16473 3/20 0.38
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
GNAO1 P09471 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CCR3 P51677 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13850082 0.90 ALDH1A1 (0.60) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL26505364 0.89 ALDH1A1 (0.50) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL10282362 0.85 ALDH1A1 (0.54) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL22691916 0.82 ALDH1A1 (0.60) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL4569260 0.80 ALDH1A1 (0.48) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL22123358 0.80 ALDH1A1 (0.48) ALDH1A1PKMPOLBSMN1; SMN2TSHR
SCHEMBL4500757 0.80 GNAO1 (0.49) ALDH1A1PKMMAPTTSHRGNAO1
SCHEMBL240458 0.80 ALDH1A1 (0.58) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL18173166 0.80 ALDH1A1 (0.58) ALDH1A1PKMPOLBSMN1; SMN2MAPT
SCHEMBL15308547 0.76 ALDH1A1 (0.52) ALDH1A1PKMPOLBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-3189091-A2 MAIN CHAIN POLYAMINES Genzyme Corporation (US) 2017-07-12 EP disclosed
US-20170182087-A1 MAIN CHAIN POLYAMINES GENZYME CORPORATION (US) 2017-06-29 US disclosed
WO-2016007821-A2 MAIN CHAIN POLYAMINES GENZYME CORPORATION (US) 2016-01-14 WO disclosed
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
EP-1090930-B1 POLYMERIZATION METHOD KANEKA CORP (JP) 2005-05-04 EP disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed
EP-1090930-A1 POLYMERIZATION METHOD KANEKA CORPORATION (JP) 2001-04-11 EP disclosed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
US-6033825-A CONTAINING A HYDRAZINE COMPOUND AND A CONTRAST-BOOSTING AMINO COMPOUND AND/OR PHOSPHONIUM COMPOUND, AND THE SILVER HALIDE EMULSION LAYER OR IN A LAYER IN A REACTIVE RELATIONSHIP THEREWITH, CONTAINS A VINYLLACTAM POLYMER AGFA-GEVAERT NV (BE) 2000-03-07 US disclosed
US-5622137-A FOR USE IN TESTING COOKED FOODS TRANS WORLD SERVICES (US) 1997-04-22 US disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170182087-A1 MAIN CHAIN POLYAMINES SRM, SMS, ODC1 ALDH1A1 3155/4885PKM 1302/4885POLB 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.