Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3155303 | 0.83 | OPRM1 (0.36) | OPRM1OPRD1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL4389539 | 0.78 | SMN1; SMN2 (0.41) | CYP2D6HPGDMEN1CYP1A2CYP3A4 | |
| SCHEMBL4393093 | 0.74 | NTRK1 (0.34) | SLC6A2 | |
| SCHEMBL30763451 | 0.73 | ALDH1A1 (0.47) | CYP2D6HPGDMEN1CYP1A2CYP3A4 | |
| SCHEMBL28702630 | 0.71 | HTT (0.42) | HPGDKMT2AHTTSMN1; SMN2 | |
| SCHEMBL14562358 | 0.69 | TNF (0.43) | TNFSLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL14364509 | 0.68 | OPRM1 (0.32) | TNFOPRM1OPRD1BACE1 | |
| SCHEMBL28455188 | 0.68 | — | — | |
| SCHEMBL28685310 | 0.68 | KDM1A (0.32) | — | |
| SCHEMBL22858501 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799657-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2009-12-02 | — | — | EP | disclosed |
| US-7465805-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| US-20080051287-A1 | Isoxazoline Derivatives and Their Use as Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1799657-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037945-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051287-A1 | Isoxazoline Derivatives and Their Use as Herbicides | CYP4X1, CYP3A7, CYP4Z1 | TNF 4509/4885OPRM1 2731/4885OPRD1 2644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.