Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156745 | 0.91 | PRKCA (0.44) | PRKCAMMP12KDM4EALDH1A1GAA | |
| SCHEMBL13476321 | 0.85 | PRKCA (0.42) | PRKCAMMP12KDM4EALDH1A1GAA | |
| SCHEMBL2156763 | 0.82 | PRKCA (0.54) | PRKCAMMP12KDM4EALDH1A1GAA | |
| SCHEMBL3079634 | 0.80 | PRKCA (0.71) | PRKCAMMP12ALDH1A1TSHR | |
| SCHEMBL3080762 | 0.80 | PRKCA (0.71) | PRKCAMMP12ALDH1A1TSHR | |
| SCHEMBL4394875 | 0.77 | PRKCA (0.33) | PRKCAMMP12KDM4EALDH1A1HPGD | |
| SCHEMBL2156572 | 0.76 | PRKCA (0.49) | PRKCAMMP12KDM4EALDH1A1GAA | |
| SCHEMBL4382196 | 0.75 | NOTUM (0.42) | KDM4EALDH1A1HPGDNOTUM | |
| SCHEMBL394438 | 0.75 | PRKCA (0.60) | PRKCAMMP12KDM4EALDH1A1HPGD | |
| SCHEMBL2157307 | 0.75 | ALDH1A1 (0.40) | PRKCAMMP12KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ZC3HAV1, HAVCR2, ZC3HAV1L | PRKCA 3320/4885MMP12 4441/4885KDM4E 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.