Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157106 | 0.90 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDHSD17B10CDK5 | |
| SCHEMBL4382196 | 0.82 | NOTUM (0.42) | NOTUMKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL2156486 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1LMNATP53POLB | |
| SCHEMBL13476321 | 0.81 | PRKCA (0.42) | PRKCAMMP12NOTUMKDM4EALDH1A1 | |
| SCHEMBL2156837 | 0.79 | KDM4E (0.34) | PRKCAMMP12NOTUMKDM4EALDH1A1 | |
| SCHEMBL4388398 | 0.77 | PRKCA (0.48) | PRKCAMMP12NOTUMKDM4EALDH1A1 | |
| SCHEMBL13476327 | 0.76 | SIGMAR1 (0.34) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL4389329 | 0.76 | SIGMAR1 (0.34) | PRKCAMMP12NOTUMKDM4EALDH1A1 | |
| SCHEMBL13476296 | 0.76 | SIGMAR1 (0.34) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL2156552 | 0.76 | TP53 (0.34) | PRKCAMMP12NOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-04-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ZC3HAV1, HAVCR2, ZC3HAV1L | PRKCA 3320/4885MMP12 4441/4885NOTUM 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.