Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156837 | 0.86 | KDM4E (0.34) | NOTUMKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4389329 | 0.83 | SIGMAR1 (0.34) | NOTUMKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4394875 | 0.82 | PRKCA (0.33) | NOTUMKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4390041 | 0.82 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNAHPGDPOLB | |
| SCHEMBL13476321 | 0.82 | PRKCA (0.42) | NOTUMKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4387692 | 0.81 | MMP12 (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL4383179 | 0.80 | KDM4E (0.32) | NOTUMKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL2156557 | 0.80 | PRKCA (0.39) | KDM4EALDH1A1LMNA | |
| SCHEMBL2156306 | 0.80 | KDM4E (0.42) | KDM4ELMNAPOLB | |
| SCHEMBL4382706 | 0.80 | DHODH (0.32) | NOTUMKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-04-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ZC3HAV1, HAVCR2, ZC3HAV1L | NOTUM 4789/4885KDM4E 3275/4885ALDH1A1 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.