Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438897 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP2C19GAAUBE2NCYP1A2 | |
| SCHEMBL443194 | 0.86 | GAA (0.37) | ALDH1A1CYP2C19GAAUBE2NCYP1A2 | |
| SCHEMBL443195 | 0.86 | GAA (0.37) | ALDH1A1CYP2C19GAAUBE2NCYP1A2 | |
| SCHEMBL4776743 | 0.83 | CYP2C19 (0.42) | ALDH1A1CYP2C19GAAUBE2NCYP1A2 | |
| SCHEMBL14303404 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP2C19GAASMN1; SMN2POLB | |
| SCHEMBL442815 | 0.78 | GAA (0.40) | ALDH1A1CYP2C19GAAUBE2NSMN1; SMN2 | |
| SCHEMBL442814 | 0.78 | GAA (0.40) | ALDH1A1CYP2C19GAAUBE2NSMN1; SMN2 | |
| SCHEMBL29988261 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1GAASMN1; SMN2TP53CHRNB2 | |
| SCHEMBL22173500 | 0.76 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2TP53PEPD | |
| SCHEMBL460036 | 0.75 | ALDH1A1 (0.37) | ALDH1A1CYP2C19CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | ALDH1A1 272/4885CYP2C19 3016/4885GAA 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.