SCHEMBL4389

SCHEMBL4389

C[C](C)C1CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269368 0.92
SCHEMBL5281 0.89
SCHEMBL5131 0.89 CES2 (0.47)
SCHEMBL9978895 0.89 CES2 (0.47)
SCHEMBL5411 0.89 CES2 (0.47)
SCHEMBL5421 0.84
SCHEMBL4889848 0.83 TSHR (0.45)
SCHEMBL10790644 0.83 EPHX1 (0.35)
SCHEMBL7827736 0.77 NOS2 (0.40)
SCHEMBL10791887 0.76 AAK1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204407-B1 PROCESS GIVAUDAN SA (CH) 2024-06-19 EP claimed
US-20230312506-A1 PROCESS GIVAUDAN SA (CH) 2023-10-05 US claimed
CN-116535460-A Sulfur-containing peptidomimetic compounds, and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2023-08-04 CN claimed
EP-4204407-A1 PROCESS Givaudan SA (CH) 2023-07-05 EP claimed
CN-116209659-A Method 奇华顿股份有限公司 2023-06-02 CN claimed
WO-2014108487-A1 P-STEREOGENIC CHIRAL PRECURSOR OF CHIRAL LIGANDS AND USE THEREOF UNIVERSITE D'AIX-MARSEILLE (FR) 2014-07-17 WO claimed
WO-2007129111-A1 DIAZEPINE DERIVATIVES AS 5-HT2A ANTAGONISTS MERCK SHARP & DOHME LIMITED (GB) 2007-11-15 WO claimed
US-4713477-A ANTISECRETORY AGENTS G. D. SEARLE & CO. (US) 1987-12-15 US claimed
EP-4204407-B1 PROCESS GIVAUDAN SA (CH) 2024-06-19 EP disclosed
US-20240139087-A1 ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS GIVAUDAN SA (CH) 2024-05-02 US disclosed
US-20240132487-A1 SUBSTITUTED AZACYLES AS TRMP8 MODULATORS GIVAUDAN SA (CH) 2024-04-25 US disclosed
EP-4291553-A1 ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS Givaudan SA (CH) 2023-12-20 EP disclosed
US-20230312506-A1 PROCESS GIVAUDAN SA (CH) 2023-10-05 US disclosed
CN-116535460-A Sulfur-containing peptidomimetic compounds, and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2023-08-04 CN disclosed
US-5032616-A Plants TRACOR, INC. 1991-07-16 US disclosed
EP-0377139-A1 N-substituted acylamino acid compounds, process for their production and their use Banyu Pharmaceutical Co., Ltd. (JP) 1990-07-11 EP disclosed
EP-0258853-B1 4-SUBSTITUTED CYCLOHEXYLAMINE DERIVATIVES, FUNGICIDES CONTAINING THEM AND PROCESS FOR COMBATING FUNGI BASF Aktiengesellschaft (DE) 1990-07-11 EP disclosed
EP-0337637-A1 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics Sankyo Company Limited (JP) 1989-10-18 EP disclosed
EP-0258853-A1 4-Substituted cyclohexylamine derivatives, fungicides containing them and process for combating fungi BASF Aktiengesellschaft (DE) 1988-03-09 EP disclosed
US-4713477-A ANTISECRETORY AGENTS G. D. SEARLE & CO. (US) 1987-12-15 US disclosed