SCHEMBL4389213

SCHEMBL4389213

C[CH]C(=O)Oc1ccccc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.49
FABP7 O15540 1/20 0.49
FABP5 Q01469 1/20 0.49
L3MBTL1 Q9Y468 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
KDM4E B2RXH2 8/20 0.45
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 3/20 0.44
MAPK1 P28482 3/20 0.44
MAPT P10636 2/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
HTT P42858 3/20 0.43
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35121 0.82 FABP3 (0.49) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL29733244 0.82 FABP3 (0.49) FABP3FABP7FABP5L3MBTL1TDP1
Biphenyl SCHEMBL27827806 0.81 FABP3 (0.48) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL6207259 0.80 KDM4E (0.53) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL3728321 0.79 KDM4E (0.58) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL8986479 0.79 FABP3 (0.53) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL28487364 0.79 FABP3 (0.56) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL1639323 0.79 FABP3 (0.56) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL30563023 0.79 FABP3 (0.56) FABP3FABP7FABP5L3MBTL1TDP1
SCHEMBL1638833 0.79 FABP3 (0.56) FABP3FABP7FABP5L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20070054084-A1 Optical recording medium and compound used for the same MITSUI CHEMICALS, INC. (JP) 2007-03-08 US disclosed
EP-1672626-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM Mitsui Chemicals, Inc. (JP) 2006-06-21 EP disclosed
US-20050208425-A1 Imide compound and optical recording media made by using the same YAMAMOTO CHEMICALS, INC. (JP) 2005-09-22 US disclosed
EP-1445115-A1 IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 FABP3 3634/4885FABP7 1946/4885FABP5 4213/4885
US-20050208425-A1 Imide compound and optical recording media made by using the same CRY1, MTNR1A, TRPA1 FABP3 4779/4885FABP7 4827/4885FABP5 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.