SCHEMBL438962

SCHEMBL438962

C=C(C)C(=O)COS(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300353 0.78
Fluoride SCHEMBL27598849 0.76 CA2 (0.30) CA2
SCHEMBL27723205 0.75
SCHEMBL10794666 0.75 TSHR (0.32) TSHR
SCHEMBL18692048 0.75 FNTA (0.41) ALDH1A1TSHR
Methacrylic Acid SCHEMBL1133554 0.71 CA1 (0.36) CA2ALDH1A1TSHR
SCHEMBL7605882 0.70
SCHEMBL92311 0.70
Glycinebetaine SCHEMBL21522630 0.70 MEN1 (0.30)
SCHEMBL28696663 0.70 FNTA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3777836-A1 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES ALLERGAN, INC. (US) 2021-02-17 EP claimed
EP-2952178-B1 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES ALLERGAN INC (US) 2020-09-02 EP claimed
EP-2952178-A1 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES ALLERGAN, INC. (US) 2015-12-09 EP claimed
EP-1811959-B1 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES ALLERGAN INC (US) 2015-09-02 EP claimed
US-5130389-A Sulfonate anion monomer, a comonomer and a crosslinking agent for improving absorbancy of paper towels or disposable diapers PHILLIPS PETROLEUM COMPANY (US) 1992-07-14 US claimed
US-5075399-A Highly absorbent to aqueous electrolyte solutions PHILLIPS PETROLEUM COMPANY (US) 1991-12-24 US claimed
US-11903986-B2 Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye AKRIVISTA LLC (US) 2024-02-20 US disclosed
EP-1811959-B2 OPHTHALMIC COMPOSITIONS ALLERGAN INC (US) 2022-06-15 EP disclosed
US-20210251961-A1 COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING SAME ALLERGAN INC (US) 2021-08-19 US disclosed
EP-3777836-A1 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES ALLERGAN, INC. (US) 2021-02-17 EP disclosed
EP-2952178-B1 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES ALLERGAN INC (US) 2020-09-02 EP disclosed
US-20200069576-A1 COMPOSITIONS CONTAINING ALPHA-2-ADRENERGIC AGONIST COMPONENTS ALLERGAN INC (US) 2020-03-05 US disclosed
EP-3500344-A1 METHODS OF DIAGNOSING AND TREATING DRY EYE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE Akrivista, LLC (US) 2019-06-26 EP disclosed
WO-1998030248-A2 COMPOSITIONS AND METHODS FOR STORING CONTACT LENSES ALLERGAN SALES, INC. (US) 1998-07-16 WO disclosed
EP-0835142-A1 COMPOSITIONS AND METHODS FOR DISINFECTING A CONTACT LENS AND DETECTING THE PRESENCE OF AN OXIDATIVE DISINFECTANT Allergan (US) 1998-04-15 EP disclosed
WO-1998005365-A2 COMPOSITIONS AND METHODS FOR DISINFECTING CONTACT LENSES AND PRESERVING CONTACT LENS CARE PRODUCTS ALLERGAN SALES, INC. (US) 1998-02-12 WO disclosed
US-5703024-A AQUEOUS SOLUTION CONTAINING HYDROGEN PEROXIDE, REDOX ACTIVE TRANSITION METAL COMPOUND AS COLOR INDICATOR, POLYANIONIC COMPONENT TO PREVENT STAINING OF LENS IMMERSED IN SOLUTION ALLERGAN (US) 1997-12-30 US disclosed
US-5648074-A POLYANIONIC COMPOUND, CHLORINE DIOXIDE ALLERGAN (US) 1997-07-15 US disclosed
WO-1997002053-A1 COMPOSITIONS AND METHODS FOR DISINFECTING A CONTACT LENS AND DETECTING THE PRESENCE OF AN OXIDATIVE DISINFECTANT ALLERGAN (US) 1997-01-23 WO disclosed
US-5075399-A Highly absorbent to aqueous electrolyte solutions PHILLIPS PETROLEUM COMPANY (US) 1991-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210251961-A1 COMPOSITIONS FOR DELIVERY OF THERAPEUTICS INTO THE EYES AND METHODS FOR MAKING AND USING SAME MUC1, EPCAM, MYOC CA2 1279/4885ALDH1A1 2009/4885TDP1 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.