Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 10/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | GMNN | O75496 | 4/20 | 0.34 |
| ▸ | APEX1 | P27695 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 4/20 | 0.34 |
| ▸ | BLM | P54132 | 4/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439814 | 0.68 | PRKCA (0.38) | PRKCASMN1; SMN2MAPTNPSR1MEN1 | |
| SCHEMBL30604783 | 0.64 | KCNH2 (0.46) | LMNAKMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL30604781 | 0.64 | KCNH2 (0.46) | LMNAKMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL4082855 | 0.63 | ALDH1A1 (0.59) | PARP1SMN1; SMN2MAPTMEN1LMNA | |
| SCHEMBL330603 | 0.63 | TSHR (0.56) | PARP1SMN1; SMN2POLBTDP1ALDH1A1 | |
| SCHEMBL31690948 | 0.62 | NR4A2 (0.47) | PARP1LMNATDP1KDM4EALDH1A1 | |
| SCHEMBL17448504 | 0.62 | AXL (0.40) | PARP1SMN1; SMN2MEN1LMNAPOLB | |
| Benzene SCHEMBL28248705 | 0.62 | TSHR (0.54) | PARP1SMN1; SMN2POLBTDP1ALDH1A1 | |
| SCHEMBL6674297 | 0.61 | BACE1 (0.37) | MEN1KMT2ARECQLALDH1A1HSD17B10 | |
| SCHEMBL16749033 | 0.61 | FFAR4 (0.38) | PARP1SMN1; SMN2POLBHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |