Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 10/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455080 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7960619 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7940151 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL31418737 | 0.74 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL22078658 | 0.72 | CASP3 (0.85) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL22033026 | 0.72 | POLB (0.67) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10916179 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL24237007 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL28948956 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6627205 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435964-B1 | NOVEL PRODRUGS OF N-H BOND-CONTAINING COMPOUNDS AND METHODS OF MAKING THEREOF | UNIV KANSAS (US) | 2009-12-09 | — | — | EP | disclosed |
| US-20030119814-A1 | Novel prodrugs of N-H bond-containing compounds and methods of making thereof | THE UNIVERSITY OF KANSAS | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119814-A1 | Novel prodrugs of N-H bond-containing compounds and methods of making thereof | CTH, CBS, GSTP1 | KDM4E 3724/4885ALDH1A1 553/4885HPGD 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.