Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408003 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| Hydrochloric Acid SCHEMBL10934502 | 0.98 | TRPA1 (0.31) | TRPA1 | |
| Maleic Acid SCHEMBL10933625 | 0.86 | HCAR2 (0.35) | — | |
| SCHEMBL2141215 | 0.77 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL1449515 | 0.77 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL207685 | 0.68 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL29286255 | 0.67 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL29901519 | 0.65 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL28240692 | 0.65 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL5637462 | 0.65 | TRPA1 (0.31) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102758-A2 | N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2024-05-16 | — | — | WO | claimed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | claimed |
| US-8153625-B2 | Nitrogen-containing heterocyclic compounds and medicinal use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-04-10 | — | — | US | claimed |
| US-8101589-B2 | Nitric oxide-releasing molecules | NOXILIZER, INC. (US) | 2012-01-24 | — | — | US | claimed |
| JP-4738352-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| US-7829553-B2 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | AMULET PHARMACEUTICALS, INC. (US) | 2010-11-09 | — | — | US | claimed |
| US-7759336-B2 | Nitrogen-containing heterocyclic compounds and medicinal use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-20 | — | — | US | claimed |
| US-20090270509-A1 | NITRIC OXIDE-RELEASING MOLECULES | NOXILIZER, INC. (US) | 2009-10-29 | — | — | US | claimed |
| US-7569559-B2 | Nitric oxide-releasing molecules | NOXILIZER, INC. (US) | 2009-08-04 | — | — | US | claimed |
| US-20070286840-A1 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | AMULET PHARMACEUTICALS, INC. | 2007-12-13 | — | — | US | claimed |
| EP-1718316-A2 | NITRIC OXIDE-RELEASING POLYMERS | Amulet Pharmaceuticals, Inc. (US) | 2006-11-08 | — | — | EP | claimed |
| EP-1718603-A2 | NITRIC OXIDE-RELEASING MOLECULES | Noxilizer, Inc. (US) | 2006-11-08 | — | — | EP | claimed |
| US-20050203069-A1 | Nitric oxide-releasing molecules | NOXILIZER, INC. | 2005-09-15 | — | — | US | claimed |
| WO-2005081752-A2 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. (US) | 2005-09-09 | — | — | WO | claimed |
| WO-2005081753-A2 | NITRIC OXIDE-RELEASING MOLECULES | NOXILIZER, INC. (US) | 2005-09-09 | — | — | WO | claimed |
| WO-1998038182-A1 | HYPOLIPIDEMIC BICYCLIC DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | claimed |
| EP-0394484-B1 | BENZOTHIADIAZEPINE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 1995-02-15 | — | — | EP | claimed |
| US-5036065-A | Antiarrythmic agents, anesthetics, calcium antagonists | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-07-30 | — | — | US | claimed |
| EP-0394484-A1 | BENZOTHIADIAZEPINE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | claimed |
| EP-0042354-B1 | IMIDAZOBENZOTHIADIAZEPINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1985-12-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270509-A1 | NITRIC OXIDE-RELEASING MOLECULES | NOS2, NOS1, NOS3 | TRPA1 630/4885 |
| US-20050203069-A1 | Nitric oxide-releasing molecules | NOS2, NOS1, NOS3 | TRPA1 630/4885 |
| US-20070286840-A1 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | NOS3, NOS2, DDT | TRPA1 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.