Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL10925110 | 0.98 | LOXL2 (0.59) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL4619209 | 0.98 | LOXL2 (0.59) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL6488374 | 0.94 | LOXL2 (0.55) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL4686835 | 0.94 | POLB (0.63) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| 4-Nitrotoluene SCHEMBL15387849 | 0.90 | ACHE (0.69) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| 4-Nitroaniline SCHEMBL27990857 | 0.90 | ALDH1A1 (0.69) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| Benzyl Bromide SCHEMBL27831169 | 0.89 | ALDH1A1 (0.60) | LOXL2CYP2C19ALDH1A1TSHRGSK3B | |
| SCHEMBL9587030 | 0.88 | CA1 (0.50) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL11245076 | 0.88 | HSPB1 (0.59) | LOXL2CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL413781 | 0.87 | SRD5A2 (0.62) | CYP2C19ALDH1A1TSHRGSK3BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6073 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058663-A | Near infrared fluorescent probe TM-N2 for detecting nitroreductase with good water solubility, and preparation method and application thereof | 陕西理工大学 | 2025-05-30 | — | — | CN | claimed |
| US-12305098-B2 | Luminescent probe and its preparation method and application | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | claimed |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | claimed |
| CN-120004899-A | Nitroreductase responsive fluorescent probe and preparation method and application thereof | 四川大学 | 2025-05-16 | — | — | CN | claimed |
| CN-120004787-A | Design, synthesis and activity research of in-situ detection nitroreductase fluorescent probe | 南京华辉天成生物医药有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-115947912-B | Preparation and application of imine porous organic framework material | 浙江理工大学 | 2025-04-25 | — | — | CN | claimed |
| CN-119841781-A | Quinazolinone-triazene compound, and preparation method and application thereof | 青岛科技大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119823027-A | Piperidinyl piperidine modified beta-carboline open ring compound, and preparation method and application thereof | 南通大学 | 2025-04-15 | — | — | CN | claimed |
| US-12275734-B1 | Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-04-15 | — | — | US | claimed |
| CN-116375643-B | Deaconitine derivative and preparation method and application thereof | 中国人民解放军海军军医大学 | 2025-04-01 | — | — | CN | claimed |
| US-5064956-A | Process for preparing mono-n-alkylated polyazamacrocycles | THE DOW CHEMICAL COMPANY (US) | 1991-11-12 | — | — | US | claimed |
| CN-1044096-A | The method for preparing the alkylating many nitrogen heterocyclic rings of list-N- | DOW CHEMICAL CO (US) | 1990-07-25 | — | — | CN | claimed |
| WO-1990007261-A2 | PROCESS FOR PREPARING MONO-N-ALKYLATED POLYAZAMACROCYCLES | THE DOW CHEMICAL COMPANY (US) | 1990-07-12 | — | — | WO | claimed |
| EP-0374929-A1 | Process for preparing mono-n-alkylated polyazamacrocycles | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| EP-0054917-B1 | 6- AND 4-SUBSTITUTED-1-AZABICYCLO(3.2.0)HEPTAN-3,7-DIONE-2-CARBOXYLATES | MERCK & CO. INC. (US) | 1988-03-09 | — | — | EP | claimed |
| US-4302580-A | Process for the production of a cephamycin derivative | MEIJI SEIKA KAISHA, LTD. (JP) | 1981-11-24 | — | — | US | claimed |
| US-4257915-A | USE IN PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | claimed |
| US-4228096-A | BY AMIDATING THEN QUATERNIZING | THE DOW CHEMICAL COMPANY (US) | 1980-10-14 | — | — | US | claimed |
| US-3993704-A | Para-nitrobenzotribromide process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-23 | — | — | US | claimed |
| US-3984253-A | Imaging processes and elements therefor | EASTMAN KODAK COMPANY (US) | 1976-10-05 | — | — | US | claimed |