Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167477 | 0.79 | TP53 (0.35) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL13903579 | 0.77 | HTT (0.43) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL13903831 | 0.77 | PKM (0.37) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL10167480 | 0.77 | TP53 (0.37) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL13903622 | 0.76 | RET (0.38) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL13903578 | 0.75 | RET (0.40) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL10167427 | 0.75 | LMNA (0.39) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL10167500 | 0.74 | HTT (0.37) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL13903608 | 0.74 | LMNA (0.39) | MAPTHPGDKDM4EGAAHTT | |
| SCHEMBL13903619 | 0.73 | NPC1 (0.40) | MAPTHPGDKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |