Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | NMT1 | P30419 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437947 | 0.88 | KMT2A (0.53) | MAPK1MAPTKMT2AMEN1GAA | |
| SCHEMBL437781 | 0.87 | MAPT (0.61) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL439008 | 0.87 | NMT2 (0.60) | MAPK1MAPTKMT2AMEN1GAA | |
| SCHEMBL439271 | 0.87 | MAPK1 (0.65) | MAPK1MAPTKMT2AMEN1GAA | |
| SCHEMBL441687 | 0.87 | KMT2A (0.62) | MAPK1MAPTKMT2AMEN1GAA | |
| SCHEMBL438203 | 0.86 | MAPT (0.62) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL1467161 | 0.85 | MAPK1 (0.65) | MAPK1MAPTKMT2AMEN1GAA | |
| SCHEMBL1467189 | 0.84 | MAPK1 (0.63) | MAPK1MAPTKMT2AMEN1GAA | |
| SCHEMBL621322 | 0.84 | NMT1 (0.54) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL620981 | 0.84 | NMT1 (0.53) | MAPK1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |