Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NMT2 | O60551 | 1/20 | 0.49 |
| ▸ | NMT1 | P30419 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367417 | 0.87 | MEN1 (0.65) | KMT2AMEN1MAPK10MAPTGAA | |
| SCHEMBL438198 | 0.87 | MAPK1 (0.63) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL437947 | 0.86 | KMT2A (0.53) | KMT2AMEN1MAPK10MAPTGAA | |
| SCHEMBL10991178 | 0.86 | MEN1 (0.64) | KMT2AMEN1MAPK10MAPTGAA | |
| SCHEMBL30900718 | 0.86 | MEN1 (0.64) | KMT2AMEN1MAPK10MAPTGAA | |
| SCHEMBL27252854 | 0.86 | MEN1 (0.64) | KMT2AMEN1MAPK10MAPTGAA | |
| SCHEMBL439008 | 0.85 | NMT2 (0.60) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL439271 | 0.85 | MAPK1 (0.65) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL437781 | 0.85 | MAPT (0.61) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL438203 | 0.84 | MAPT (0.62) | KMT2AMEN1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |