Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7976828 | 0.92 | HRH3 (0.36) | HRH3 | |
| SCHEMBL4384169 | 0.85 | ALDH1A1 (0.48) | KCNH2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL4379690 | 0.82 | KMT2A (0.52) | KCNH2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4381291 | 0.81 | HRH4 (0.35) | KCNH2HRH3PTPN1HPGDALDH1A1 | |
| SCHEMBL4381289 | 0.81 | HRH4 (0.35) | KCNH2HRH3PTPN1HPGDALDH1A1 | |
| SCHEMBL4380966 | 0.80 | NQO1 (0.45) | KCNH2HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7961327 | 0.80 | RAB9A (0.43) | KCNH2HRH3HPGDMEN1ALDH1A1 | |
| SCHEMBL7987297 | 0.80 | HRH3 (0.54) | KCNH2HRH3CYP3A4CYP2C9HPGD | |
| SCHEMBL4381458 | 0.80 | GAA (0.40) | KCNH2HRH3MEN1KMT2A | |
| SCHEMBL4376189 | 0.78 | KCNH2 (0.37) | KCNH2HRH3CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |