Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390107 | 0.92 | KCNH2 (0.38) | HRH3 | |
| SCHEMBL4384169 | 0.81 | ALDH1A1 (0.48) | — | |
| Oxalic Acid SCHEMBL7990912 | 0.81 | MEN1 (0.47) | HRH3PPARA | |
| Oxalic Acid SCHEMBL7991422 | 0.80 | HRH2 (0.39) | HRH3 | |
| SCHEMBL4379690 | 0.78 | KMT2A (0.52) | — | |
| Oxalic Acid SCHEMBL7991342 | 0.77 | LMNA (0.54) | — | |
| SCHEMBL4381291 | 0.77 | HRH4 (0.35) | HRH3PPARAHRH4PPARG | |
| SCHEMBL4381289 | 0.77 | HRH4 (0.35) | HRH3PPARAHRH4PPARG | |
| SCHEMBL7987181 | 0.77 | GAA (0.55) | HRH3PPARAHRH4PPARG | |
| Oxalic Acid SCHEMBL7987116 | 0.76 | L3MBTL1 (0.49) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | claimed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |