Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436527 | 1.00 | TSHR (0.45) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL12574578 | 1.00 | TSHR (0.45) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL436526 | 1.00 | TSHR (0.45) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL26260732 | 0.94 | TSHR (0.41) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL19297387 | 0.88 | LMNA (0.41) | ALDH1A1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL7979466 | 0.88 | MEN1 (0.37) | ALDH1A1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL10354329 | 0.86 | LMNA (0.43) | ALDH1A1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL24855332 | 0.83 | TSHR (0.62) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL22430923 | 0.83 | TSHR (0.57) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL23135368 | 0.83 | TSHR (0.39) | TSHRTP53CYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101781-B2 | Process for the preparation of highly optical pure carvedilol | AHN-GOOK PHARMACEUTICAL CO., LTD. (KR) | 2012-01-24 | — | — | US | disclosed |
| US-20090176992-A1 | PROCESS FOR THE PREPARATION OF HIGHLY OPTICAL PURE CARVEDILOL | RSTECH CORPORATION (KR) | 2009-07-09 | — | — | US | disclosed |
| WO-2007097504-A1 | PROCESS FOR THE PREPARATION OF HIGHLY OPTICAL PURE CARVEDILOL | AHN-GOOK PHARMACEUTICAL CO., LTD. (KR) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176992-A1 | PROCESS FOR THE PREPARATION OF HIGHLY OPTICAL PURE CARVEDILOL | ADRB2, ADRB1, ADRB3 | TSHR 525/4885TP53 4761/4885CYP3A4 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.