Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390636 | 0.81 | NR3C1 (0.53) | NR3C1 | |
| SCHEMBL476762 | 0.81 | NR3C1 (0.67) | NR3C1 | |
| SCHEMBL12663246 | 0.80 | NR3C1 (0.54) | NR3C1CCR1 | |
| SCHEMBL4399769 | 0.78 | NR3C1 (0.52) | NR3C1 | |
| SCHEMBL4404083 | 0.75 | NR3C1 (0.41) | NR3C1CCR1CYP17A1CYP1A2 | |
| SCHEMBL476811 | 0.74 | NR3C1 (0.69) | NR3C1 | |
| SCHEMBL476766 | 0.73 | NR3C1 (0.66) | NR3C1 | |
| SCHEMBL4386491 | 0.72 | NR3C1 (0.60) | NR3C1CCR1CYP17A1CYP1A2 | |
| SCHEMBL4400814 | 0.72 | NR3C1 (0.54) | NR3C1 | |
| SCHEMBL4400812 | 0.72 | NR3C1 (0.47) | NR3C1CCR1CYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081910-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043789-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |