SCHEMBL4390830

SCHEMBL4390830

[CH2]C(=O)Oc1ccccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.56
PPARG P37231 1/20 0.51
TDP1 Q9NUW8 2/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
NOTUM Q6P988 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064558 0.82 TDP1 (0.50) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL29351165 0.82 TDP1 (0.50) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL236664 0.82 TDP1 (0.50) BCHEPPARGTDP1ATML3MBTL1
Ethylene SCHEMBL28138082 0.81 PTGS2 (0.55) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL577353 0.80 PPARG (0.53) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL172737 0.80 PTGS2 (0.59) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL30179347 0.80 PTGS2 (0.59) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL5932986 0.80 TDP1 (0.49) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL650229 0.79 ELANE (0.50) BCHEPPARGTDP1ATML3MBTL1
SCHEMBL27726032 0.79 TDP1 (0.49) BCHEPPARGTDP1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
EP-1640804-B1 Positive-tone radiation-sensitive resin composition JSR CORP (JP) 2008-11-19 EP disclosed
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-7335457-B2 Positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-02-26 US disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
CN-1311988-C Imide compounds and optical recording media made by using the same MITSUI CHEMICALS INC (JP) 2007-04-25 CN disclosed
US-20070054084-A1 Optical recording medium and compound used for the same MITSUI CHEMICALS, INC. (JP) 2007-03-08 US disclosed
CN-1867980-A Optical recording medium and compound for use in the same MITSUI CHEMICALS INC (JP) 2006-11-22 CN disclosed
EP-1640804-A2 Positive-tone radiation-sensitive resin composition JSR Corporation (JP) 2006-03-29 EP disclosed
US-20050208425-A1 Imide compound and optical recording media made by using the same YAMAMOTO CHEMICALS, INC. (JP) 2005-09-22 US disclosed
CN-1575236-A Imide compounds and optical recording media made by using the same MITSUI CHEMICALS INC OGISO AKI (JP) 2005-02-02 CN disclosed
EP-1445115-A1 IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-08-11 EP disclosed
WO-2004052841-A1 CARBIDOPA PRODRUGS AND USES THEREOF XENOPORT, INC. (US) 2004-06-24 WO disclosed
US-4652648-A STABILIZERS FOR HEAT, OXIDATION AND LIGHT CIBA-GEIGY CORPORATION (US) 1987-03-24 US disclosed
US-4579682-A HEAT, OXYGEN, AND LIGHT PROTECTION FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed
EP-0042359-B1 PHOSPHONOUS-ACID MONOESTER MONOAMIDE AND ORGANIC POLYMERS STABILIZED THEREWITH CIBA-GEIGY AG (CH) 1984-10-31 EP disclosed
US-4434109-A STABILIZERS AGAINST HEAT, OXYGEN AND LIGHT CIBA-GEIGY CORPORATION (US) 1984-02-28 US disclosed
EP-0042359-A1 Phosphonous-acid monoester monoamide and organic polymers stabilized therewith CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 BCHE 615/4885PPARG 4759/4885TDP1 4127/4885
US-20050208425-A1 Imide compound and optical recording media made by using the same CRY1, MTNR1A, TRPA1 BCHE 4078/4885PPARG 3291/4885TDP1 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.