Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | PLG | P00747 | 7/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | PLAT | P00750 | 6/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4384614 | 0.84 | KMT2A (0.54) | MEN1KMT2APLGKLK1ALDH1A1 | |
| SCHEMBL9302652 | 0.78 | PLAU (0.48) | KMT2APLAUF2PLGPRSS1 | |
| SCHEMBL7563090 | 0.77 | FTO (0.48) | NCEH1MEN1KMT2APLAUF2 | |
| SCHEMBL7563955 | 0.77 | FTO (0.48) | PLAUF2PLGPRSS1PLAT | |
| SCHEMBL4005710 | 0.75 | MAPT (0.53) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4104661 | 0.74 | KMT2A (0.59) | MEN1KMT2APLAUPRSS1ALDH1A1 | |
| SCHEMBL11668983 | 0.74 | SLC6A3 (0.51) | MEN1KMT2APLAUF2PLG | |
| Hydrochloric Acid SCHEMBL7865524 | 0.74 | MAPT (0.52) | MEN1KMT2APRSS1KDM4EALDH1A1 | |
| SCHEMBL7320953 | 0.74 | PLAU (0.45) | MEN1KMT2APLAUF2PLG | |
| SCHEMBL7321809 | 0.73 | SLC6A3 (0.65) | MEN1KMT2APRSS1KLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129056-A1 | TREATMENT FOR RESPIRATORY DISEASE | Mucokinetica Ltd. (GB) | 2017-02-15 | — | — | EP | claimed |
| WO-2015155515-A1 | TREATMENT FOR RESPIRATORY DISEASE | MUCOKINETICA LIMITED (GB) | 2015-10-15 | — | — | WO | claimed |
| EP-2124926-A1 | TREATMENT FOR RESPIRATORY DISEASE | Mucokinetica Ltd. (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008090366-A1 | TREATMENT FOR RESPIRATORY DISEASE | MUCOKINETICA LTD. (GB) | 2008-07-31 | — | — | WO | disclosed |