Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.52 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.49 |
| ▸ | HINT1 | P49773 | 5/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL8024691 | 0.95 | P2RY2 (0.56) | P2RY2P2RY4P2RY6GSK3ARPS6KA3 | |
| Guanosine SCHEMBL27658690 | 0.92 | RNASEL (0.51) | P2RY2P2RY4P2RY6GSK3ARPS6KA3 | |
| Uridine SCHEMBL3345043 | 0.87 | SLC28A1 (0.64) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Guanosine SCHEMBL19437743 | 0.87 | HPGD (0.62) | GSK3ARPS6KA3MAPK14HPGDHINT1 | |
| Guanosine SCHEMBL8995759 | 0.87 | HPGD (0.62) | GSK3ARPS6KA3MAPK14HPGDHINT1 | |
| Guanosine SCHEMBL625261 | 0.87 | SLC28A1 (0.65) | P2RY2P2RY4P2RY6GSK3ARPS6KA3 | |
| Adenosine SCHEMBL15753116 | 0.86 | ADORA3 (0.56) | GSK3ARPS6KA3MAPK14SLC28A1SLC28A2 | |
| Inosine SCHEMBL23209720 | 0.86 | SLC29A1 (0.47) | GSK3ARPS6KA3MAPK14HPGDSLC28A1 | |
| Guanosine SCHEMBL29045171 | 0.86 | HPGD (0.60) | GSK3ARPS6KA3MAPK14HPGDHINT1 | |
| Guanosine SCHEMBL8024690 | 0.85 | P2RY2 (0.57) | P2RY2P2RY4P2RY6GSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021043-A1 | Nucleic Acids Comprising formula (NuGlXmGnNv)a and Derivatives Thereof as Immunostimulating Agent/Adjuvant | CureVac GmbHÛ (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20110250225-A1 | COMPOSITION COMPRISING A COMPLEXED (M)RNA AND A NAKED MRNA FOR PROVIDING OR ENHANCING AN IMMUNOSTIMULATORY RESPONSE IN A MAMMAL AND USES THEREOF | CUREVAC GMBH | 2011-10-13 | — | — | US | disclosed |
| EP-2331129-A1 | COMPOSITION COMPRISING A COMPLEXED (M)RNA AND A NAKED MRNA FOR PROVIDING OR ENHANCING AN IMMUNOSTIMULATORY RESPONSE IN A MAMMAL AND USES THEREOF | Curevac GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |